Description
Human MCTS1 Recombinant Protein (N-His)
Human MCTS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys181, with an N-terminal His tag. Predicted molecular weight: 22.72 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Malignant T-cell-amplified sequence 1 (MCTS1) is a ~20 kDa protein. Translation regulator forming a complex with DENR to promote translation reinitiation. For research use only.
Translation reinitiation is the process where the small ribosomal subunit remains attached to the mRNA following termination of translation of a regulatory upstream ORF (uORF), and resume scanning on the same mRNA molecule to initiate translation of a downstream ORF, usually the main ORF (mORF). The MCTS1/DENR complex is pivotal to two linked mechanisms essential for translation reinitiation. Firstly, the dissociation of deacylated tRNAs from post-termination 40S ribosomal complexes during ribosome recycling. Secondly, the recruitment in an EIF2-independent manner of aminoacylated initiator tRNA to P site of 40S ribosomes for a new round of translation.
| Product Name: | Human MCTS1 Recombinant Protein (N-His) |
| SKU: | GXRP03060 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MCTS1, Multiple copies T-cell malignancies, MCT1, MCT-1, Malignant T-cell-amplified sequence 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys181 |
| Calculated MW: | 22.72 kDa |
| UniProt: | Q9ULC4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
