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Human MICA ELISA Kit

SKU:
HUFI00015
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q29983
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Sandwich ELISA, Double Antibody
Synonyms:
MICA, MIC-A
Reactivity:
Human
€599
Frequently bought together:

Description

Human MICA ELISA Kit

MICA is a cell-surface glycoprotein that is structurally similar to MHC class I. MICA plays a key role in governing the activation threshold of innate and adaptive arms of the immune system by presenting self-antigens to T cells. Thus MICA functions as a "tumor escape molecule" in that it presents antigens from tumors to T cells. MICA functions in a similar way as MHC class I, but unlike MICA, the MHC class I molecule is able to bind peptides only from cytosolic proteins. MICA functions to activate NK cells and T cells that express the NKG2D receptor to kill tumor cells. MICA also functions in natural killer (NK) cell-mediated cytotoxicity by triggering a non-conventional pathway of CTL activation. The Assay Genie MICA ELISA kit is a highly sensitive assay for the quantitative measurement of MICA in serum, blood, plasma, cell culture supernatant, and tissue samples.

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