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Human MPO Recombinant Protein (N-His)
Key Features

Human MPO Recombinant Protein (N-His) (GXRP00592)

SKU GXRP00592
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human MPO Recombinant Protein (N-His)

Human MPO Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val165-Gly278, with an N-terminal His tag. Predicted molecular weight: 15.16 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. For research use only.

It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.

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