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Human MX1 Recombinant Protein (N-His)
Key Features

Human MX1 Recombinant Protein (N-His) (GXRP01156)

SKU GXRP01156
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human MX1 Recombinant Protein (N-His)

Human MX1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu366-Thr636, with an N-terminal His tag. Predicted molecular weight: 34.67 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interferon-induced GTP-binding protein Mx1 is a ~75 kDa protein. Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. For research use only.

Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress.

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