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Human NAP1L1 Recombinant Protein (N-His)
Key Features

Human NAP1L1 Recombinant Protein (N-His) (GXRP04867)

SKU GXRP04867
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human NAP1L1 Recombinant Protein (N-His)

Human NAP1L1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg72-Glu356, with an N-terminal His tag. Predicted molecular weight: 35.65 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nucleosome assembly protein 1-like 1 (NAP1L1) is a ~45 kDa protein. Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. For research use only.

Also participates in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Also stimulates homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis. Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development.

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