Description
Human NEIL1 Recombinant Protein (N-His)
Human NEIL1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser43-Ala314, with an N-terminal His tag. Predicted molecular weight: 33.21 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Endonuclease 8-like 1 (NEIL1) is a ~43 kDa protein. Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. For research use only.
Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.
| Product Name: | Human NEIL1 Recombinant Protein (N-His) |
| SKU: | GXRP02708 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Endonuclease 8-like 1, DNA glycosylase/AP lyase Neil1, Endonuclease VIII-like 1, Nei-like protein 1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Nei homolog 1, NEIL1, FPG1, NEH1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser43-Ala314 |
| Calculated MW: | 33.21 kDa |
| UniProt: | Q96FI4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
