Description
Human NFE2 Recombinant Protein (N-His)
Human NFE2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala214-Gln293, with an N-terminal His tag. Predicted molecular weight: 11.41 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Transcription factor NF-E2 45 kDa subunit is a ~41 kDa protein. Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. For research use only.
Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
| Product Name: | Human NFE2 Recombinant Protein (N-His) |
| SKU: | GXRP08616 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Transcription factor NF-E2 45 kDa subunit, Leucine zipper protein NF-E2, Nuclear factor erythroid-derived 2 45 kDa subunit, p45 NF-E2, NFE2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ala214-Gln293 |
| Calculated MW: | 11.41 kDa |
| UniProt: | Q16621 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
