Description
Human NOS1AP Recombinant Protein (N-His)
Human NOS1AP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr285-Val506, with an N-terminal His tag. Predicted molecular weight: 26.8 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (NOS1AP) is a ~56 kDa protein. Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. For research use only.
The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.
| Product Name: | Human NOS1AP Recombinant Protein (N-His) |
| SKU: | GXRP00217 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Nitric oxide synthase 1 adaptor protein, NOS1AP, C-terminal PDZ ligand of neuronal nitric oxide synthase protein, KIAA0464, CAPON, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr285-Val506 |
| Calculated MW: | 26.8 kDa |
| UniProt: | O75052 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
