Description
Human NOX4 Recombinant Protein (N-His)
Human NOX4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly210-Glu424, with an N-terminal His tag. Predicted molecular weight: 27.1 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. NADPH oxidase 4 (NOX4) is a ~66 kDa protein. NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2. For research use only.
Can also catalyze to a smaller extent, the reduction of oxygen to superoxide. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
| Product Name: | Human NOX4 Recombinant Protein (N-His) |
| SKU: | GXRP02921 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | RENOX, NOX4, Renal NAD(P)H-oxidase, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly210-Glu424 |
| Calculated MW: | 27.1 kDa |
| UniProt: | Q9NPH5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
