Description
Human NPHP4 Recombinant Protein (N-His)
Human NPHP4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning His1171-Gln1426, with an N-terminal His tag. Predicted molecular weight: 31.27 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nephrocystin-4 (NPHP4) is a ~157 kDa protein. Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. For research use only.
Does not seem to be strictly required for ciliogenesis. Required for building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Seems to recruit INT to basal bodies of motile cilia which subsequently interacts with actin-modifying proteins such as DAAM1.
| Product Name: | Human NPHP4 Recombinant Protein (N-His) |
| SKU: | GXRP05531 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA0673, Nephrocystin-4, NPHP4, Nephroretinin |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | His1171-Gln1426 |
| Calculated MW: | 31.27 kDa |
| UniProt: | O75161 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
