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Human ORC2 Recombinant Protein (N-His)
Key Features

Human ORC2 Recombinant Protein (N-His) (GXRP13761)

SKU GXRP13761
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ORC2 Recombinant Protein (N-His)

Human ORC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser282-Ala577, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Origin recognition complex subunit 2 is a ~65 kDa protein. Component of the origin recognition complex (ORC) that binds origins of replication. For research use only.

DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3.

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