Description
Human OTUD3 Recombinant Protein (N-His)
Human OTUD3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly46-Lys220, with an N-terminal His tag. Predicted molecular weight: 22.34 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. OTU domain-containing protein 3 is a ~45 kDa protein. Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. For research use only.
Also hydrolyzes heterotypic (mixed and branched) and homotypic chains. Important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation.
| Product Name: | Human OTUD3 Recombinant Protein (N-His) |
| SKU: | GXRP09376 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | OTU domain-containing protein 3; 3.4.19.12; OTUD3; KIAA0459 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly46-Lys220 |
| Calculated MW: | 22.34 kDa |
| UniProt: | Q5T2D3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
