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Human PA2G4 Recombinant Protein (N-His)
Key Features

Human PA2G4 Recombinant Protein (N-His) (GXRP03089)

SKU GXRP03089
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human PA2G4 Recombinant Protein (N-His)

Human PA2G4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser2-Asp394, with an N-terminal His tag. Predicted molecular weight: 45.95 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Proliferation-associated protein 2G4 (PA2G4) is a ~43 kDa protein. May play a role in a ERBB3-regulated signal transduction pathway. For research use only.

Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA.

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