Description
Human PACSIN2 Recombinant Protein (N-His)
Human PACSIN2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val21-Gly293, with an N-terminal His tag. Predicted molecular weight: 34.41 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein kinase C and casein kinase substrate in neurons protein 2 is a ~55 kDa protein. Regulates the morphogenesis and endocytosis of caveolae. For research use only.
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. Essential for endothelial organization in sprouting angiogenesis, modulates CDH5-based junctions. 1. de Kreuk, BJ. et al. (2011) Journal of cell science 124, 2375-88. PMID: 21693584 2. de Kreuk, BJ. et al. (2012) The Journal of biological chemistry 287, 43438-53. PMID: 23129763 3. Goh, SL. et al. (2012) PloS one 7, e51628. PMID: 23236520 4. Giridharan, SS. et al. (2013) Molecular biology of the cell 24, 1776-90, S1-15. PMID: 23596323
| Product Name: | Human PACSIN2 Recombinant Protein (N-His) |
| SKU: | GXRP12013 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PACSIN2, Protein kinase C and casein kinase substrate in neurons protein 2, SdpII, Syndapin-2, Syndapin-II |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val21-Gly293 |
| Calculated MW: | 34.41 kDa |
| UniProt: | Q9UNF0 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
