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Human PAPSS2 Recombinant Protein (N-His)
Key Features

Human PAPSS2 Recombinant Protein (N-His) (GXRP09773)

SKU GXRP09773
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human PAPSS2 Recombinant Protein (N-His)

Human PAPSS2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu231-Asn614, with an N-terminal His tag. Predicted molecular weight: 46.21 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 is a ~69 kDa protein. Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. For research use only.

The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth.

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