Description
Human PAX6 Recombinant Protein (N-His)
Human PAX6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg272, with an N-terminal His tag. Predicted molecular weight: 32.8 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Paired box protein Pax-6 (PAX6) is a ~46 kDa protein. Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. For research use only.
Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Acts as a transcriptional repressor of NFATC1-mediated gene expression.
| Product Name: | Human PAX6 Recombinant Protein (N-His) |
| SKU: | GXRP01309 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | AN2, Aniridia type II protein, Oculorhombin, PAX6, Paired box protein Pax-6 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg272 |
| Calculated MW: | 32.8 kDa |
| UniProt: | P26367 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
