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Human PBRM1 Recombinant Protein (N-His)
Key Features

Human PBRM1 Recombinant Protein (N-His) (GXRP02516)

SKU GXRP02516
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human PBRM1 Recombinant Protein (N-His)

Human PBRM1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning His1152-Gly1273, with an N-terminal His tag. Predicted molecular weight: 16.59 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein polybromo-1 (PBRM1) is a ~192 kDa protein. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). For research use only.

Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.

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