Description
Human PDCD4/PD4 Recombinant Protein (N-His)
Human PDCD4/PD4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe164-Tyr469, with an N-terminal His tag. Predicted molecular weight: 36.58 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Programmed cell death protein 4 (PDCD4/PD4) is a ~51 kDa protein. Inhibits translation initiation and cap-dependent translation. For research use only.
May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription.
| Product Name: | Human PDCD4/PD4 Recombinant Protein (N-His) |
| SKU: | GXRP04074 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PDCD4, Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, Protein 197/15a, H731, Programmed cell death protein 4 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe164-Tyr469 |
| Calculated MW: | 36.58 kDa |
| UniProt: | Q53EL6 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
