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Human PDHB Recombinant Protein (N-His)
Key Features

Human PDHB Recombinant Protein (N-His) (GXRP00868)

SKU GXRP00868
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human PDHB Recombinant Protein (N-His)

Human PDHB Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu31-Asn341, with an N-terminal His tag. Predicted molecular weight: 36.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) is a ~39 kDa protein. Together with PDHA1 forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex. For research use only.

The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle (Probable). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase (E3) (Probable). The E1 subunit catalyzes both the thiamine pyrophosphate (TPP)-dependent decarboxylation of pyruvate and the reductive acetylation of a lipoyl group covalently linked to the lipoyl-bearing domains of E2.

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