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Human PEA15 Recombinant Protein (N-His)
Key Features

Human PEA15 Recombinant Protein (N-His) (GXRP09578)

SKU GXRP09578
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human PEA15 Recombinant Protein (N-His)

Human PEA15 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ala130, with an N-terminal His tag. Predicted molecular weight: 17.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Astrocytic phosphoprotein PEA-15 is a ~15 kDa protein. Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. For research use only.

Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.

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