Description
Human PGRMC2 Recombinant Protein (N-His)
Human PGRMC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly67-Asp223, with an N-terminal His tag. Predicted molecular weight: 20.09 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Membrane-associated progesterone receptor component 2 is a ~23 kDa protein. Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. For research use only.
May serve as a universal non-classical progesterone receptor in the uterus (Probable). Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1.
| Product Name: | Human PGRMC2 Recombinant Protein (N-His) |
| SKU: | GXRP11158 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DG6, Membrane-associated progesterone receptor component 2, PGRMC2, PMBP, Progesterone membrane-binding protein, Steroid receptor protein DG6 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly67-Asp223 |
| Calculated MW: | 20.09 kDa |
| UniProt: | O15173 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
