Description
Human PIDD1 Recombinant Protein (N-His)
Human PIDD1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe694-Arg885, with an N-terminal His tag. Predicted molecular weight: 23.79 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. p53-induced death domain-containing protein 1 (PIDD1) is a ~99 kDa protein. Component of the DNA damage/stress response pathway that functions downstream of p53/TP53 and can either promote cell survival or apoptosis. For research use only.
Associated with CRADD and the CASP2 caspase, it forms the PIDDosome a complex that activates CASP2 and triggers apoptosis. Associated with IKBKG and RIPK1, it enhances sumoylation and ubiquitination of IKBKG which is important for activation of the transcription factor NF-kappa-B.
| Product Name: | Human PIDD1 Recombinant Protein (N-His) |
| SKU: | GXRP02881 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Leucine-rich repeat and death domain-containing protein, PIDD1, p53-induced death domain-containing protein 1, PIDD, LRDD |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe694-Arg885 |
| Calculated MW: | 23.79 kDa |
| UniProt: | Q9HB75 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
