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Human PIK3AP1 Recombinant Protein (N-His)
Key Features

Human PIK3AP1 Recombinant Protein (N-His) (GXRP02485)

SKU GXRP02485
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human PIK3AP1 Recombinant Protein (N-His)

Human PIK3AP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu489-Ser730, with an N-terminal His tag. Predicted molecular weight: 30.02 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1) is a ~90 kDa protein. Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. For research use only.

Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

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