Description
Human PLA2G5 Recombinant Protein (N-His)
Human PLA2G5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly21-Ser138, with an N-terminal His tag. Predicted molecular weight: 15.88 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phospholipase A2 group V is a ~15 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. For research use only.
Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), preferentially releasing fatty acyl groups with a low degree of unsaturation such as oleoyl (C18:1) and linoleoyl (C18:2) groups. Hydrolyzes low-density lipoprotein (LDL) phospholipids releasing unsaturated fatty acids that drive macrophage polarization toward an M2 phenotype. May act in an autocrine and paracrine manner. Contributes to lipid remodeling of cellular membranes at different subcellular locations and generation of lipid mediators involved in pathogen clearance.
| Product Name: | Human PLA2G5 Recombinant Protein (N-His) |
| SKU: | GXRP09149 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly21-Ser138 |
| Calculated MW: | 15.88 kDa |
| UniProt: | P39877 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
