Description
Human PLAA Recombinant Protein (N-His)
Human PLAA Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu162-Ala312, with an N-terminal His tag. Predicted molecular weight: 19.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phospholipase A-2-activating protein (PLAA) is a ~87 kDa protein. Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. For research use only.
Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.
| Product Name: | Human PLAA Recombinant Protein (N-His) |
| SKU: | GXRP03104 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PLAP, PLA2P, Phospholipase A-2-activating protein, PLAA |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu162-Ala312 |
| Calculated MW: | 19.17 kDa |
| UniProt: | Q9Y263 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
