Description
Human PLXNB2 Recombinant Protein (N-His)
Human PLXNB2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln56-Gly225, with an N-terminal His tag. Predicted molecular weight: 20.74 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Plexin-B2 is a ~205 kDa protein. Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. For research use only.
Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Also acts as a cell surface receptor for angiogenin (ANG); promoting ANG endocytosis and translocation to the cytoplasm or nucleus. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development.
| Product Name: | Human PLXNB2 Recombinant Protein (N-His) |
| SKU: | GXRP11066 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA0315, MM1, PLXNB2, Plexin-B2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln56-Gly225 |
| Calculated MW: | 20.74 kDa |
| UniProt: | O15031 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
