Description
Human PREX2 Recombinant Protein (N-His)
Human PREX2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp880-Val1240, with an N-terminal His tag. Predicted molecular weight: 43.07 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein is a ~182 kDa protein. Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. For research use only.
Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
| Product Name: | Human PREX2 Recombinant Protein (N-His) |
| SKU: | GXRP11440 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DEP domain-containing protein 2, DEPDC2, P-Rex2, PREX2, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein, PtdIns(3,4,5)-dependent Rac exchanger 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp880-Val1240 |
| Calculated MW: | 43.07 kDa |
| UniProt: | Q70Z35 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
