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Human PRICKLE1 Recombinant Protein (N-His)
Key Features

Human PRICKLE1 Recombinant Protein (N-His) (GXRP04913)

SKU GXRP04913
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human PRICKLE1 Recombinant Protein (N-His)

Human PRICKLE1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg41-Ser327, with an N-terminal His tag. Predicted molecular weight: 34.61 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Prickle-like protein 1 (PRICKLE1) is a ~94 kDa protein. Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. For research use only.

Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.

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