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Human PRICKLE3 Recombinant Protein (N-His)
Key Features

Human PRICKLE3 Recombinant Protein (N-His) (GXRP11217)

SKU GXRP11217
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human PRICKLE3 Recombinant Protein (N-His)

Human PRICKLE3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala60-Thr373, with an N-terminal His tag. Predicted molecular weight: 37.89 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Prickle planar cell polarity protein 3 is a ~68 kDa protein. Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation. For research use only.

PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module. Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions. Involved in the organization of the basal body. Involved in cilia growth and positioning.

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