Description
Human PTPN4 Recombinant Protein (N-His)
Human PTPN4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp636-Lys926, with an N-terminal His tag. Predicted molecular weight: 35.55 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tyrosine-protein phosphatase non-receptor type 4 is a ~105 kDa protein. Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. For research use only.
Regulates neuronal cell homeostasis by protecting neurons against apoptosis. Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction. Also dephosphorylates the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway. May act at junctions between the membrane and the cytoskeleton.
| Product Name: | Human PTPN4 Recombinant Protein (N-His) |
| SKU: | GXRP09214 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Tyrosine-protein phosphatase non-receptor type 4; 3.1.3.48; Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1; PTPN4 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp636-Lys926 |
| Calculated MW: | 35.55 kDa |
| UniProt: | P29074 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
