Description
Human PTPRB Recombinant Protein (N-His)
Human PTPRB Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala1655-Asp1918, with an N-terminal His tag. Predicted molecular weight: 32.69 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Receptor-type tyrosine-protein phosphatase beta (PTPRB) is a ~224 kDa protein. Plays an important role in blood vessel remodeling and angiogenesis. For research use only.
Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth.
| Product Name: | Human PTPRB Recombinant Protein (N-His) |
| SKU: | GXRP01250 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | R-PTP-beta, Receptor-type tyrosine-protein phosphatase beta, PTPB, Vascular endothelial protein tyrosine phosphatase, VE-PTP, Protein-tyrosine phosphatase beta, PTPRB |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ala1655-Asp1918 |
| Calculated MW: | 32.69 kDa |
| UniProt: | P23467 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
