Description
Human PTPRQ Recombinant Protein (N-His)
Human PTPRQ Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg1929-Met2299, with an N-terminal His tag. Predicted molecular weight: 59.90 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phosphatidylinositol phosphatase PTPRQ is a ~260 kDa protein. Dephosphorylates phosphatidylinositol phosphates, such as phosphatidylinositol 3,4,5-trisphosphate (PIP3) and phosphatidylinositol 3,5-diphosphates, with preference for PIP3. For research use only.
Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity in vitro; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by regulating the levels of PIP3 in MSCs and preadipocyte cells.
| Product Name: | Human PTPRQ Recombinant Protein (N-His) |
| SKU: | GXRP06754 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Phosphatidylinositol phosphatase PTPRQ, R-PTP-Q, PTP-RQ, PTPRQ, Receptor-type tyrosine-protein phosphatase Q |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg1929-Met2299 |
| Calculated MW: | 59.90 kDa |
| UniProt: | Q9UMZ3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
