Description
Human RANBP1 Recombinant Protein (N-His)
Human RANBP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp44-Gln201, with an N-terminal His tag. Predicted molecular weight: 20.74 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ran-specific GTPase-activating protein is a ~23 kDa protein. Plays a role in RAN-dependent nucleocytoplasmic transport. For research use only.
Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus. Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L.
| Product Name: | Human RANBP1 Recombinant Protein (N-His) |
| SKU: | GXRP11307 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | RANBP1, Ran-binding protein 1, Ran-specific GTPase-activating protein, RanBP1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp44-Gln201 |
| Calculated MW: | 20.74 kDa |
| UniProt: | P43487 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
