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Human RAP2A Recombinant Protein (N-His)
Key Features

Human RAP2A Recombinant Protein (N-His) (GXRP07536)

SKU GXRP07536
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human RAP2A Recombinant Protein (N-His)

Human RAP2A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Gln183, with an N-terminal His tag. Predicted molecular weight: 22.78 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ras-related protein Rap-2a (RAP2A) is a ~20 kDa protein. Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. For research use only.

In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and regulates cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

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