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Human REL Recombinant Protein (N-His)
Key Features

Human REL Recombinant Protein (N-His) (GXRP09444)

SKU GXRP09444
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human REL Recombinant Protein (N-His)

Human REL Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Glu283, with an N-terminal His tag. Predicted molecular weight: 34.64 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Proto-oncogene c-Rel is a ~68 kDa protein. Proto-oncogene that may play a role in differentiation and lymphopoiesis. For research use only.

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

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