Description
Human RNF6 Recombinant Protein (N-His-SUMO)
Human RNF6 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Thr580-Gly685, with an N-terminal His-SUMO tag. Predicted molecular weight: 24.42 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase RNF6 is a ~78 kDa protein. E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. For research use only.
Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator. Mediates polyubiquitination of QKI in macrophages, leading to its degradation.
| Product Name: | Human RNF6 Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP04723 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | RNF6, E3 ubiquitin-protein ligase RNF6, SPG2, RING-type E3 ubiquitin transferase RNF6 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Thr580-Gly685 |
| Calculated MW: | 24.42 kDa |
| UniProt: | Q9Y252 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
