Description
Human RXRA Recombinant Protein (N-His)
Human RXRA Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr223-Thr462, with an N-terminal His tag. Predicted molecular weight: 29.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Retinoic acid receptor RXR-alpha (RXRA) is a ~50 kDa protein. Receptor for retinoic acid that acts as a transcription factor. For research use only.
Forms homo- or heterodimers with retinoic acid receptors (RARs) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 to regulate transcription. The high affinity ligand for retinoid X receptors (RXRs) is 9-cis retinoic acid. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone deacetylation, chromatin condensation and transcriptional suppression.
| Product Name: | Human RXRA Recombinant Protein (N-His) |
| SKU: | GXRP04273 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Retinoid X receptor alpha, RXRA, Nuclear receptor subfamily 2 group B member 1, NR2B1, Retinoic acid receptor RXR-alpha |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr223-Thr462 |
| Calculated MW: | 29.12 kDa |
| UniProt: | P19793 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
