Description
Human S100A1 Recombinant Protein (N-His)
Human S100A1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser94, with an N-terminal His tag. Predicted molecular weight: 12.71 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein S100-A1 (S100A1) is a ~10 kDa protein. Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation. For research use only.
In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes. These changes allow interactions with specific target proteins and modulate their activity. Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca(2+)-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole.
| Product Name: | Human S100A1 Recombinant Protein (N-His) |
| SKU: | GXRP01244 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | S100A1, Protein S100-A1, S-100 protein alpha chain, S100 calcium-binding protein A1, S100A, S-100 protein subunit alpha |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ser94 |
| Calculated MW: | 12.71 kDa |
| UniProt: | P23297 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
