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Human Serpin B6 ELISA Kit

SKU:
HUFI01081
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P35237
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
SERPINB6, Serpin B6, Placental thrombin inhibitor, Cytoplasmic antiproteinase, CAP, Peptidase inhibitor 6, PI-6, PI6, PTI, CAP, SPI3, deafness, autosomal recessive 91, DFNB91, MSTP057, serpin peptidase inhibitor, clade B, ovalbumin, member 6, proteas
Reactivity:
Human
Research Area:
Cell Biology
€599
Frequently bought together:

Description

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Human Serpin B6 ELISA Kit

Serpin B6 belongs to the ovalbumin(ov)-serpin subfamily of the serpin (serine proteinase inhibitor) superfamily. Serpin B6 was first discovered as a thrombin inhibitor in the placenta. The mouse homolog was discovered to be expressed in inner ear hair cells. Nonsyndromic progressive hearing loss is linked to mutations in Serpin B6 , implying that this serpin plays an important role in the inner ear in preventing lysosomal content leakage during stress, and that loss of this protection leads to cell death and sensorineural hearing loss.