Description
Human SLC10A1 Recombinant Protein (N-His)
Human SLC10A1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ala349, with an N-terminal His tag. Predicted molecular weight: 40.28 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Hepatic sodium/bile acid cotransporter (SLC10A1) is a ~38 kDa protein. As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. For research use only.
It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.
| Product Name: | Human SLC10A1 Recombinant Protein (N-His) |
| SKU: | GXRP02289 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Cell growth-inhibiting gene 29 protein, Sodium/taurocholate cotransporting polypeptide, NTCP, SLC10A1, Sodium/bile acid cotransporter, Na(+)/taurocholate transport protein, Solute carrier family 10 member 1, Na(+)/bile acid cotransporter |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ala349 |
| Calculated MW: | 40.28 kDa |
| UniProt: | Q14973 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
