Description
Human SLC12A3 Recombinant Protein (N-His)
Human SLC12A3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu3-Cys146, with an N-terminal His tag. Predicted molecular weight: 18.14 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Solute carrier family 12 member 3 (SLC12A3) is a ~113 kDa protein. Electroneutral sodium and chloride ion cotransporter, which acts as a key mediator of sodium and chloride reabsorption in kidney distal convoluted tubules. For research use only.
Also acts as a receptor for the pro-inflammatory cytokine IL18, thereby contributing to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2. May act either independently of IL18R1, or in a complex with IL18R1.
| Product Name: | Human SLC12A3 Recombinant Protein (N-His) |
| SKU: | GXRP01818 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | TSC, SLC12A3, NCC, Solute carrier family 12 member 3, Na-Cl cotransporter, Thiazide-sensitive sodium-chloride cotransporter, Na-Cl symporter |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu3-Cys146 |
| Calculated MW: | 18.14 kDa |
| UniProt: | P55017 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
