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Human SLC16A1 Recombinant Protein (N-His)
Key Features

Human SLC16A1 Recombinant Protein (N-His) (GXRP01793)

SKU GXRP01793
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human SLC16A1 Recombinant Protein (N-His)

Human SLC16A1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn444-Val500, with an N-terminal His tag. Predicted molecular weight: 8.6 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Monocarboxylate transporter 1 (SLC16A1/MCT1) is a ~53 kDa protein. Bidirectional proton-coupled monocarboxylate transporter. For research use only.

Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH. The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate. MCT1 is a major lactate exporter. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

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