Description
Human SLC19A1 Recombinant Protein (N-His)
Human SLC19A1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu455-Gln591, with an N-terminal His tag. Predicted molecular weight: 16.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Reduced folate transporter (SLC19A1) is a ~64 kDa protein. Antiporter that mediates the import of reduced folates or a subset of cyclic dinucleotides, driven by the export of organic anions. For research use only.
Acts as an importer of immunoreactive cyclic dinucleotides, such as cyclic GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol, and its linkage isomer 3'-3'-cGAMP, thus playing a role in triggering larger immune responses. Mechanistically, acts as a secondary active transporter, which exports intracellular organic anions down their concentration gradients to facilitate the uptake of its substrates. Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate. Also mediates the import of antifolate drug methotrexate.
| Product Name: | Human SLC19A1 Recombinant Protein (N-His) |
| SKU: | GXRP01576 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Intestinal folate carrier 1, FOLT, Solute carrier family 19 member 1, RFC1, hSLC19A1, IFC-1, SLC19A1, RFT-1, FLOT1, RFC, Placental folate transporter, Reduced folate transporter 1, Reduced folate transporter, Reduced folate carrier protein, hRFC |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu455-Gln591 |
| Calculated MW: | 16.35 kDa |
| UniProt: | P41440 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
