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Human SMC2 Recombinant Protein (N-His)
Key Features

Human SMC2 Recombinant Protein (N-His) (GXRP07463)

SKU GXRP07463
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human SMC2 Recombinant Protein (N-His)

Human SMC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn473-Ser673, with an N-terminal His tag. Predicted molecular weight: 24.77 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Structural maintenance of chromosomes protein 2 (SMC2) is a ~135 kDa protein. Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. For research use only.

The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

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