Description
Human SMPDL3B Recombinant Protein (N-His)
Human SMPDL3B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly21-Gly433, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Acid sphingomyelinase-like phosphodiesterase 3b is a ~50 kDa protein. Lipid-modulating phosphodiesterase. For research use only.
Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro).
| Product Name: | Human SMPDL3B Recombinant Protein (N-His) |
| SKU: | GXRP13088 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ASM-like phosphodiesterase 3b, ASML3B, ASMLPD, Acid sphingomyelinase-like phosphodiesterase 3b, EC:3.1.4.-, SMPDL3B |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly21-Gly433 |
| UniProt: | Q92485 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
