Description
Human SMUG1 Recombinant Protein (N-His)
Human SMUG1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser26-Lys270, with an N-terminal His tag. Predicted molecular weight: 29.58 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Single-strand selective monofunctional uracil DNA glycosylase is a ~29 kDa protein. Recognizes base lesions in the genome and initiates base excision DNA repair. For research use only.
Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent.
| Product Name: | Human SMUG1 Recombinant Protein (N-His) |
| SKU: | GXRP09663 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Single-strand selective monofunctional uracil DNA glycosylase; 3.2.2.-; SMUG1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser26-Lys270 |
| Calculated MW: | 29.58 kDa |
| UniProt: | Q53HV7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
