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Human SRA1 Recombinant Protein (N-His)
Key Features

Human SRA1 Recombinant Protein (N-His) (GXRP06412)

SKU GXRP06412
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human SRA1 Recombinant Protein (N-His)

Human SRA1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu108-Ser236, with an N-terminal His tag. Predicted molecular weight: 16.90 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Steroid receptor RNA activator 1 (SRA1) is a ~24 kDa protein. Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. For research use only.

Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.

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