Description
Human SRY Recombinant Protein (N-His)
Human SRY Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu204, with an N-terminal His tag. Predicted molecular weight: 26.05 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sex-determining region Y protein (SRY) is a ~23 kDa protein. Transcriptional regulator that controls a genetic switch in male development. For research use only.
It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.
| Product Name: | Human SRY Recombinant Protein (N-His) |
| SKU: | GXRP02052 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | TDF, Sex-determining region Y protein, Testis-determining factor, SRY |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu204 |
| Calculated MW: | 26.05 kDa |
| UniProt: | Q05066 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
