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Human SUPV3L1 Recombinant Protein (N-His)
Key Features

Human SUPV3L1 Recombinant Protein (N-His) (GXRP07650)

SKU GXRP07650
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human SUPV3L1 Recombinant Protein (N-His)

Human SUPV3L1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr47-Glu722, with an N-terminal His tag. Predicted molecular weight: 78.21 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent RNA helicase SUPV3L1, mitochondrial is a ~87 kDa protein. Major helicase player in mitochondrial RNA metabolism. For research use only.

Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates.

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