Description
Human TG Recombinant Protein (N-His)
Human TG Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser2083-Ala2333, with an N-terminal His tag. Predicted molecular weight: 29.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Thyroglobulin (TG) is a ~304 kDa protein. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). For research use only.
The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.
| Product Name: | Human TG Recombinant Protein (N-His) |
| SKU: | GXRP00421 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Thyroglobulin, Tg, TG |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser2083-Ala2333 |
| Calculated MW: | 29.63 kDa |
| UniProt: | P01266 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
